The emerging roles and functions of circular RNAs and their generation

Abstract Circular RNAs (circRNAs) are closed long non-coding RNAs, in which the 5’ and 3’ termini are covalently linked by back-splicing of exons from a single pre-mRNA. Emerging evidence indicates that circRNAs are broadly expressed in mammalian cells and show cell type- or tissue-specific expressi...

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Bibliographic Details
Main Authors: Chun-Ying Yu, Hung-Chih Kuo
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Biomedical Science
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12929-019-0523-z