Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet

Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet

Abstract Background Exposure to traffic-generated emissions is associated with the development and exacerbation of inflammatory lung disorders such as chronic obstructive pulmonary disorder (COPD) and idiopathic pulmonary fibrosis (IPF). Although many lung diseases show an expansion of Proteobacteri...

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Bibliographic Details
Main Authors: Sarah Daniel, Danielle Phillippi, Leah J. Schneider, Kayla N. Nguyen, Julie Mirpuri, Amie K. Lund
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Particle and Fibre Toxicology
Subjects:
Diesel particulate matter
Lung microbiome
Inflammation
Probiotics
Reactive oxygen species
Reactive nitrogen species
Online Access:https://doi.org/10.1186/s12989-020-00393-9

Internet

https://doi.org/10.1186/s12989-020-00393-9

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