SALL4 induces radioresistance in nasopharyngeal carcinoma via the ATM/Chk2/p53 pathway

SALL4 induces radioresistance in nasopharyngeal carcinoma via the ATM/Chk2/p53 pathway

Abstract Radiotherapy is the mainstay and primary curative treatment modality in nasopharyngeal carcinoma (NPC), whose efficacy is limited by the development of intrinsic and acquired radioresistance. Thus, deciphering new molecular targets and pathways is essential for enhancing the radiosensitivit...

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Bibliographic Details
Main Authors: Xin Nie, Ergang Guo, Cheng Wu, Dongbo Liu, Wei Sun, Linli Zhang, Guoxian Long, Qi Mei, Kongming Wu, Huihua Xiong, Guoqing Hu
Format: Article
Language:English
Published: Wiley 2019-04-01
Series:Cancer Medicine
Subjects:
apoptosis
cell cycle
nasopharyngeal carcinoma
radioresistance
SALL4
Online Access:https://doi.org/10.1002/cam4.2056

Internet

https://doi.org/10.1002/cam4.2056

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