TLR3 and TLR9 agonists improve postexposure vaccination efficacy of live smallpox vaccines.

Eradication of smallpox and discontinuation of the vaccination campaign resulted in an increase in the percentage of unvaccinated individuals, highlighting the need for postexposure efficient countermeasures in case of accidental or deliberate viral release. Intranasal infection of mice with ectrome...

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Bibliographic Details
Main Authors: Tomer Israely, Sharon Melamed, Hagit Achdout, Noam Erez, Boaz Politi, Trevor Waner, Shlomo Lustig, Nir Paran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4211728?pdf=render