Moderate Hypothermia Effectively Alleviates Acetaminophen-Induced Liver Injury With Prolonged Action Beyond Cooling

Acetaminophen (APAP) overdose accounts for the highest incidence of acute liver failure, despite the availability of an antidote i.e. N-acetylcysteine. This calls for alternative strategies to manage APAP-induced liver injury (AILI). Therapeutic hypothermia has been explored in past studies for hepa...

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Bibliographic Details
Main Authors: Yeong Lan Tan, Siew Min Tey, Han Kiat Ho
Format: Article
Language:English
Published: SAGE Publishing 2020-11-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325820970846