The dry powder formulation of mixed cross-linked dextran microspheres and tetanus toxoid-loaded trimethyl chitosan nanospheres as a potent adjuvant for nasal delivery system

The dry powder formulation of mixed cross-linked dextran microspheres and tetanus toxoid-loaded trimethyl chitosan nanospheres as a potent adjuvant for nasal delivery system

Objective(s): The present study aimed to determine the immunoadjuvant efficacy of mixed cross-linked dextran microspheres (CDM) and tetanus toxoid (TT)-loaded trimethyl chitosan (TMC) nanospheres in dry powder form. Materials and Methods: The TMC nanoparticles (NPs) containing TT were produced using...

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Bibliographic Details
Main Authors: Mona Kabiri, Haleh Bolourian, Solmaz Dehghan, Mohsen Tafaghodi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2021-01-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
cross
linked dextran microspheres mucosal immunity nasal immunization systemic responses tetanus toxoid trimethyl chitosan nanoparticles
Online Access:https://ijbms.mums.ac.ir/article_16939_20d0effb12228d4f495bd5aa520b8ddc.pdf

Internet

https://ijbms.mums.ac.ir/article_16939_20d0effb12228d4f495bd5aa520b8ddc.pdf

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