Molecular mechanisms of regulatory action of heat shock protein 27 kDa in the apoptosis of tumor cells

Score mRNA expression and the level of Hsp27 (Heat shock protein 27) and phospho-Hsp27 in tumor cell line Jurkat and THP-1, as well as in mononuclear leukocytes obtained from healthy donors was investigated. In tumor cells, Jurkat and THP-1 Hsp27 plays the role of inhibitor of apoptosis, by influenc...

Full description

Bibliographic Details
Main Author: Ye. V. Kaigorodova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2011-08-01
Series:Bûlleten' Sibirskoj Mediciny
Subjects:
Online Access:https://bulletin.tomsk.ru/jour/article/view/1429