The potential for crizotinib in non-small cell lung cancer: a perspective review
Tyrosine kinases have a crucial role as key regulators of signaling pathways that influence cell differentiation and growth. Dysregulation of tyrosine kinase-mediated signaling is understood to be an important oncogenic driver. Genetic rearrangements involving the tyrosine kinase anaplastic lymphoma...
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2011-11-01
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Series: | Therapeutic Advances in Medical Oncology |
Online Access: | https://doi.org/10.1177/1758834011419002 |