The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci

The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci

Multidrug-resistant Streptococcus pneumoniae emerge through the modification of core genome loci by interspecies homologous recombinations, and acquisition of gene cassettes. Both occurred in the otherwise contrasting histories of the antibiotic-resistant S. pneumoniae lineages PMEN3 and PMEN9. A si...

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Bibliographic Details
Main Authors: Joshua C D'Aeth, Mark PG van der Linden, Lesley McGee, Herminia de Lencastre, Paul Turner, Jae-Hoon Song, Stephanie W Lo, Rebecca A Gladstone, Raquel Sá-Leão, Kwan Soo Ko, William P Hanage, Robert F Breiman, Bernard Beall, Stephen D Bentley, Nicholas J Croucher, The GPS Consortium
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
streptococcus pneumoniae
AMR
recombination
genomics
epidemiology
Online Access:https://elifesciences.org/articles/67113

Internet

https://elifesciences.org/articles/67113

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