α−Calcitonin gene-related peptide inhibits autophagy and calpain systems and maintains the stability of neuromuscular junction in denervated muscles

α−Calcitonin gene-related peptide inhibits autophagy and calpain systems and maintains the stability of neuromuscular junction in denervated muscles

Objective: Although it is well established that a-calcitonin gene-related peptide (CGRP) stabilizes muscle-type cholinergic receptors nicotinic subunits (AChR), the underlying mechanism by which this neuropeptide regulates muscle protein metabolism and neuromuscular junction (NMJ) morphology is uncl...

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Bibliographic Details
Main Authors: Juliano Machado, Wilian A. Silveira, Dawit A. Gonçalves, Aline Zanatta Schavinski, Muzamil M. Khan, Neusa M. Zanon, Mauricio Berriel Diaz, Rüdiger Rudolf, Isis C. Kettelhut, Luiz C. Navegantes
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819302546

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http://www.sciencedirect.com/science/article/pii/S2212877819302546

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