Inhibition of Murine Cytomegalovirus Infection in Animals by RNase P-Associated External Guide Sequences
External guide sequence (EGS) RNAs are associated with ribonuclease P (RNase P), a tRNA processing enzyme, and represent promising agents for gene-targeting applications as they can direct RNase-P-mediated cleavage of a target mRNA. Using murine cytomegalovirus (MCMV) as a model system, we examined...
Main Authors: | Wei Li, Jingxue Sheng, Mengqiong Xu, Gia-Phong Vu, Zhu Yang, Yujun Liu, Xu Sun, Phong Trang, Sangwei Lu, Fenyong Liu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-12-01
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Series: | Molecular Therapy: Nucleic Acids |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2162253117302688 |
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