Holographic Imaging of Insect Cell Cultures: Online Non-Invasive Monitoring of Adeno-Associated Virus Production and Cell Concentration

The insect cell-baculovirus vector system has become one of the favorite platforms for the expression of viral vectors for vaccination and gene therapy purposes. As it is a lytic system, it is essential to balance maximum recombinant product expression with harvest time, minimizing product exposure...

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Bibliographic Details
Main Authors: Daniel A. M. Pais, Paulo R. S. Galrão, Anastasiya Kryzhanska, Jérémie Barbau, Inês A. Isidro, Paula M. Alves
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Processes
Subjects:
Online Access:https://www.mdpi.com/2227-9717/8/4/487