PENK inhibits osteosarcoma cell migration by activating the PI3K/Akt signaling pathway

PENK inhibits osteosarcoma cell migration by activating the PI3K/Akt signaling pathway

Abstract Background This article reports the effects of proenkephalin (PENK) on osteosarcoma (OS) cell migration. Methods A Gene Expression Omnibus (GEO) dataset was used to identify differentially expressed genes (DEGs) in OS tumor samples and normal human osteoblasts. Tumor tissue and adjacent nor...

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Bibliographic Details
Main Authors: Hai-ping Zhang, Zi-liang Yu, Bing-bing Wu, Fa-rui Sun
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
PENK
Osteosarcoma
PI3K
Akt
Migration
Online Access:http://link.springer.com/article/10.1186/s13018-020-01679-6

Internet

http://link.springer.com/article/10.1186/s13018-020-01679-6

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