Link between Primate Lentiviral Coreceptor Usage and Nef Function

Link between Primate Lentiviral Coreceptor Usage and Nef Function

Simian immunodeficiency virus (SIVsmm) infection of sooty mangabeys (Cercocebus atys) is characterized by stable CD4+ T cell counts despite high plasma levels of CCR5-tropic viruses. However, in rare instances, SIVsmm acquires CXCR4 coreceptor tropism and causes severe CD4+ T cell depletion, albeit...

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Bibliographic Details
Main Authors: Jan Schmökel, Hui Li, Asma Shabir, Hangxing Yu, Matthias Geyer, Guido Silvestri, Donald L. Sodora, Beatrice H. Hahn, Frank Kirchhoff
Format: Article
Language:English
Published: Elsevier 2013-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713006128

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http://www.sciencedirect.com/science/article/pii/S2211124713006128

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