Link between Primate Lentiviral Coreceptor Usage and Nef Function
Simian immunodeficiency virus (SIVsmm) infection of sooty mangabeys (Cercocebus atys) is characterized by stable CD4+ T cell counts despite high plasma levels of CCR5-tropic viruses. However, in rare instances, SIVsmm acquires CXCR4 coreceptor tropism and causes severe CD4+ T cell depletion, albeit...
Main Authors: | Jan Schmökel, Hui Li, Asma Shabir, Hangxing Yu, Matthias Geyer, Guido Silvestri, Donald L. Sodora, Beatrice H. Hahn, Frank Kirchhoff |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-11-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124713006128 |
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