Direct Regulation of the T Cell Antigen Receptor's Activity by Cholesterol

Direct Regulation of the T Cell Antigen Receptor's Activity by Cholesterol

Biological membranes consist of hundreds of different lipids that together with the embedded transmembrane (TM) proteins organize themselves into small nanodomains. In addition to this function of lipids, TM regions of proteins bind to lipids in a very specific manner, but the function of these TM r...

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Bibliographic Details
Main Authors: Salma Pathan-Chhatbar, Carina Drechsler, Kirsten Richter, Anna Morath, Wei Wu, Bo OuYang, Chenqi Xu, Wolfgang W. Schamel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cholesterol
lipid
TCR
signaling
T cell
nanocluster
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.615996/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.615996/full

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