Epigenetic mechanisms in breast cancer therapy and resistance

Endocrine therapy has been the mainstay for hormone responsive breast cancer treatment. Here, Garcia-Martinez and colleagues discuss epigenetic mechanisms regulating ER + breast cancer and endocrine therapy resistance, and highlight approaches to rewire the cancer epigenome to improve targeted thera...

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Bibliographic Details
Main Authors: Liliana Garcia-Martinez, Yusheng Zhang, Yuichiro Nakata, Ho Lam Chan, Lluis Morey
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22024-3