Unveiling the folding mechanism of the Bromodomains

Unveiling the folding mechanism of the Bromodomains

Bromodomains (BRDs) are small protein domains often present in large multidomain proteins involved in transcriptional regulation in eukaryotic cells. They currently represent valuable targets for the development of inhibitors of aberrant transcriptional processes in a variety of human diseases. Here...

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Bibliographic Details
Main Authors: Maria Petrosino, Daniela Bonetti, Alessandra Pasquo, Laura Lori, Roberta Chiaraluce, Valerio Consalvi, Carlo Travaglini-Allocatelli
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
Bromodomain
Protein folding
Folding intermediate
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580817300845

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http://www.sciencedirect.com/science/article/pii/S2405580817300845

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