Melanogenic Inhibition and Toxicity Assessment of Flavokawain A and B on B16/F10 Melanoma Cells and Zebrafish (<i>Danio rerio</i>)

Melanogenic Inhibition and Toxicity Assessment of Flavokawain A and B on B16/F10 Melanoma Cells and Zebrafish (<i>Danio rerio</i>)

Excessive production of melanin implicates hyperpigmentation disorders. Flavokawain A (FLA) and flavokawain B (FLB) have been reported with anti-melanogenic activity, but their melanogenic inhibition and toxicity effects on the vertebrate model of zebrafish are still unknown. In the present study, c...

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Bibliographic Details
Main Authors: Nurshafika Mohd Sakeh, Nurliyana Najwa Md Razip, Farah Idayu Mohd Ma’in, Mohammad Nazri Abdul Bahari, Naimah Latif, Muhammad Nadeem Akhtar, Zetty Norhana Balia Yusof, Syahida Ahmad
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
α-MSH
B16/F10 melanoma
chalcone
flavokawain
melanogenesis
zebrafish
Online Access:https://www.mdpi.com/1420-3049/25/15/3403

Internet

https://www.mdpi.com/1420-3049/25/15/3403

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