Resident CD8(+) and migratory CD103(+) dendritic cells control CD8 T cell immunity during acute influenza infection.

Resident CD8(+) and migratory CD103(+) dendritic cells control CD8 T cell immunity during acute influenza infection.

The identification of the specific DC subsets providing a critical role in presenting influenza antigens to naïve T cell precursors remains contentious and under considerable debate. Here we show that CD8(+) T lymphocyte (TCD8+) responses are severely hampered in C57BL/6 mice deficient in the transc...

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Bibliographic Details
Main Authors: Jason Waithman, Damien Zanker, Kun Xiao, Sara Oveissi, Ben Wylie, Royce Ng, Lars Tögel, Weisan Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3672151?pdf=render

Internet

http://europepmc.org/articles/PMC3672151?pdf=render

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