Age-related decrease of miRNA-92a levels in human CD8<sup>+ </sup>T-cells correlates with a reduction of naïve T lymphocytes

<p>Abstract</p> <p>MicroRNA (miR)-17-92a expression plays a crucial role in lymphocyte ontogeny. We therefore set out to determine miR-92a expression levels in peripheral blood lymphocytes from healthy subjects to ascertain any association between these levels and ageing. We found...

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Bibliographic Details
Main Authors: Ohyashiki Michiyo, Ohyashiki Junko H, Hirota Ayako, Kobayashi Chiaki, Ohyashiki Kazuma
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Immunity & Ageing
Subjects:
Online Access:http://www.immunityageing.com/content/8/1/11