The p-i Concept: Pharmacological Interaction of Drugs With Immune Receptors
The immune response in drug hypersensitivity is normally explained by the hapten hypothesis. It postulates that drugs with a molecular weight of less than 1000 D are too small to cause an immune response per se. However, if a chemically reactive drug or drug metabolite binds covalently to a protein...
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| Format: | Article |
| Language: | English |
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Elsevier
2008-01-01
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| Series: | World Allergy Organization Journal |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1939455119305812 |