Macrophage migration inhibitory factor induces autophagy via reactive oxygen species generation.

Autophagy is an evolutionarily conserved catabolic process that maintains cellular homeostasis under stress conditions such as starvation and pathogen infection. Macrophage migration inhibitory factor (MIF) is a multifunctional cytokine that plays important roles in inflammation and tumorigenesis. C...

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Bibliographic Details
Main Authors: Yung-Chun Chuang, Wen-Hong Su, Huan-Yao Lei, Yee-Shin Lin, Hsiao-Sheng Liu, Chih-Peng Chang, Trai-Ming Yeh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3358253?pdf=render