LncRNA FTX represses the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma via regulating the M1/M2 polarization of Kupffer cells

LncRNA FTX represses the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma via regulating the M1/M2 polarization of Kupffer cells

Abstract Background The effect of lncRNA FTX on non-alcoholic fatty liver disease (NAFLD) conversion to hepatocellular carcinoma (HCC) is unclear. Methods In our study, C57BL/6 mice was fed with high fat diet for obtaining NAFLD mouse model, and diethylnitrosamine induced the formation of HCC tumor....

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Bibliographic Details
Main Authors: Huajun Wu, Zhiwei Zhong, Anji Wang, Chunhui Yuan, Ke Ning, Huanhuan Hu, Chao Wang, Xiangbao Yin
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Cancer Cell International
Subjects:
Hepatocellular carcinoma
lncRNA FTX
Non-alcoholic fatty liver disease
Kupffer cell
Online Access:http://link.springer.com/article/10.1186/s12935-020-01354-0

Internet

http://link.springer.com/article/10.1186/s12935-020-01354-0

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