Soluble human Suppression of Tumorigenicity 2 is associated with endoscopic activity in patients with moderate-to-severe ulcerative colitis treated with golimumab

Background: Suppressor of Tumorigenicity 2 (ST2) is an IL33 receptor detected in the mucosa and serum of ulcerative colitis (UC) patients. We evaluated soluble ST2 (sST2) as a surrogate biomarker of disease outcome and therapeutic response, in moderate-to-severe UC patients treated with golimumab. M...

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Main Authors: Fernando Magro, Susana Lopes, Marco Silva, Rosa Coelho, Francisco Portela, Diogo Branquinho, Luís Correia, Samuel Fernandes, Marília Cravo, Paulo Caldeira, Helena Tavares de Sousa, Marta Patita, Paula Lago, Jaime Ramos, Joana Afonso, Isabel Redondo, Patrícia Machado, George Philip, Joanne Lopes, Fátima Carneiro
Format: Article
Language:English
Published: SAGE Publishing 2019-08-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756284819869141