TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1

TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1

Emerging evidence suggests that the tripartite motif (TRIM) family play important roles in tumor development and progression. Tripartite motif-containing 50 (TRIM50) is a member of the TRIM family, but little is known regarding its expression and potential functional roles in cancer. In this study,...

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Bibliographic Details
Main Authors: Rongkun Li, Lili Zhu, Yangxizi Peng, Xiaoxin Zhang, Chunhua Dai, Dejun Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
TRIM50
tumor growth and metastasis
EMT
Snail1
pancreatic cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.695740/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.695740/full

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