High glucose upregulates connective tissue growth factor expression in human vascular smooth muscle cells

<p>Abstract</p> <p>Background</p> <p>Connective tissue growth factor (CTGF) is a potent profibrotic factor, which is implicated in fibroblast proliferation, angiogenesis and extracellular matrix (ECM) synthesis. It is a downstream mediator of some of the effects of tran...

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Bibliographic Details
Main Authors: Pan Kejian, Luo Fengming, Liu Xiaojing, Wu Wenchao, Chen Huaiqing
Format: Article
Language:English
Published: BMC 2007-01-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/8/1