Antibody-dependent enhancement infection facilitates dengue virus-regulated signaling of IL-10 production in monocytes.

Antibody-dependent enhancement infection facilitates dengue virus-regulated signaling of IL-10 production in monocytes.

Interleukin (IL)-10 levels are increased in dengue virus (DENV)-infected patients with severe disorders. A hypothetical intrinsic pathway has been proposed for the IL-10 response during antibody-dependent enhancement (ADE) of DENV infection; however, the mechanisms of IL-10 regulation remain unclear...

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Bibliographic Details
Main Authors: Tsung-Ting Tsai, Yi-Jui Chuang, Yee-Shin Lin, Chih-Peng Chang, Shu-Wen Wan, Sheng-Hsiang Lin, Chia-Ling Chen, Chiou-Feng Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4239119?pdf=render

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http://europepmc.org/articles/PMC4239119?pdf=render

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