Antiproliferative and Structure Activity Relationships of Amaryllidaceae Alkaloids

The antiproliferative activity of a set of seven natural Amaryllidaceae alkaloids and 32 derivatives against four cancer cell lines (A2780, SW1573, T47-D and WiDr) was determined. The best antiproliferative activities were achieved with alkaloids derived from pancracine (2), haemanthamine (6) and h...

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Bibliographic Details
Main Authors: Juan C. Cedrón, Ángel G. Ravelo, Leticia G. León, José M. Padrón, Ana Estévez-Braun
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Molecules
Subjects:
SAR
Online Access:http://www.mdpi.com/1420-3049/20/8/13854