A novel path-specific effect statistic for identifying the differential specific paths in systems epidemiology

Abstract Background Biological pathways play an important role in the occurrence, development and recovery of complex diseases, such as cancers, which are multifactorial complex diseases that are generally caused by mutation of multiple genes or dysregulation of pathways. Results We propose a path-s...

Full description

Bibliographic Details
Main Authors: Hongkai Li, Zhi Geng, Xiaoru Sun, Yuanyuan Yu, Fuzhong Xue
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Genetics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12863-020-00876-w