Longitudinal changes of cortical microstructure in Parkinson's disease assessed with T1 relaxometry

Background: Histological evidence suggests that pathology in Parkinson's disease (PD) goes beyond nigrostriatal degeneration and also affects the cerebral cortex. Quantitative MRI (qMRI) techniques allow the assessment of changes in brain tissue composition. However, the development and pattern...

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Bibliographic Details
Main Authors: Lucas Nürnberger, René-Maxime Gracien, Pavel Hok, Stephanie-Michelle Hof, Udo Rüb, Helmuth Steinmetz, Rüdiger Hilker, Johannes C. Klein, Ralf Deichmann, Simon Baudrexel
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:NeuroImage: Clinical
Subjects:
T1
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158216302625