Targeting the MDSCs of Tumors In Situ With Inhibitors of the MAPK Signaling Pathway to Promote Tumor Regression

Targeting the MDSCs of Tumors In Situ With Inhibitors of the MAPK Signaling Pathway to Promote Tumor Regression

Myeloid-derived suppressor cells (MDSCs) are one of the major components of the tumor microenvironment. Evidence has shown differences in the functions and fates of MDSCs in the tumor tissue and the periphery. However, the exact mechanism that regulates MDSC function has not been completely clarifie...

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Bibliographic Details
Main Authors: Jiayun Yu, Hanwen Li, Zongliang Zhang, Weimin Lin, Xiawei Wei, Bin Shao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
myeloid-derived suppressor cells
mitogen-activated protein kinases
tumor microenvironment
apoptosis
lymphocyte
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.647312/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.647312/full

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