Nitric oxide antagonizes the acid tolerance response that protects Salmonella against innate gastric defenses.
Reactive nitrogen species (RNS) derived from dietary and salivary inorganic nitrogen oxides foment innate host defenses associated with the acidity of the stomach. The mechanisms by which these reactive species exert antimicrobial activity in the gastric lumen are, however, poorly understood.The gen...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-03-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2266805?pdf=render |