Prodromal Huntington disease as a model for functional compensation of early neurodegeneration.

Functional compensation demonstrated as mechanism to offset neuronal loss in early Alzheimer disease may also occur in other adult-onset neurodegenerative diseases, particularly Huntington disease (HD) with its genetic determination and gradual changes in structural integrity. In HD, neurodegenerati...

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Bibliographic Details
Main Authors: Kathrin Malejko, Patrick Weydt, Sigurd D Süßmuth, Georg Grön, Bernhard G Landwehrmeyer, Birgit Abler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0114569