Neutralizing Anti-Hemagglutinin Monoclonal Antibodies Induced by Gene-Based Transfer Have Prophylactic and Therapeutic Effects on Influenza Virus Infection
Hemagglutinin (HA) of influenza virus is a major target for vaccines. HA initiates the internalization of the virus into the host cell by binding to host sialic acid receptors; therefore, inhibition of HA can significantly prevent influenza virus infection. However, the high diversity of HA permits...
Main Authors: | Tatsuya Yamazaki, Joe Chiba, Sachiko Akashi-Takamura |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-06-01
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Series: | Vaccines |
Subjects: | |
Online Access: | http://www.mdpi.com/2076-393X/6/3/35 |
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