Combined Therapy With Avastin, a PAF Receptor Antagonist and a Lipid Mediator Inhibited Glioblastoma Tumor Growth

Combined Therapy With Avastin, a PAF Receptor Antagonist and a Lipid Mediator Inhibited Glioblastoma Tumor Growth

Glioblastoma multiforme (GBM) is an aggressive, highly proliferative, invasive brain tumor with a poor prognosis and low survival rate. The current standard of care for GBM is chemotherapy combined with radiation following surgical intervention, altogether with limited efficacy, since survival avera...

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Bibliographic Details
Main Authors: Valerie A. Cruz Flores, Hemant Menghani, Pranab K. Mukherjee, Luis Marrero, Andre Obenaus, Quan Dang, Larissa Khoutorova, Madigan M. Reid, Ludmila Belayev, Nicolas G. Bazan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
glioma
platelet-activating factor (PAF)
lipid mediators
oncology
stroke
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.746470/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.746470/full

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