Restoration of visual function by transplantation of optogenetically engineered photoreceptors

Restoration of visual function by transplantation of optogenetically engineered photoreceptors

A challenge in cell therapy for photoreceptor degeneration is inducing the grafted cells to grow and maintain light sensitive outer segments. Here, the authors use optogenetics to circumvent this problem and restore visual function in blind mice.

Bibliographic Details
Main Authors: Marcela Garita-Hernandez, Maruša Lampič, Antoine Chaffiol, Laure Guibbal, Fiona Routet, Tiago Santos-Ferreira, Sylvia Gasparini, Oliver Borsch, Giuliana Gagliardi, Sacha Reichman, Serge Picaud, José-Alain Sahel, Olivier Goureau, Marius Ader, Deniz Dalkara, Jens Duebel
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12330-2

Internet

https://doi.org/10.1038/s41467-019-12330-2

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