Genetic and genomic perspective to understand the molecular pathogenesis of keratoconus

Genetic and genomic perspective to understand the molecular pathogenesis of keratoconus

Keratoconus (KC; Mendelian Inheritance in Man (OMIM) 14830) is a bilateral, progressive corneal defect affecting all ethnic groups around the world. It is the leading cause of corneal transplantation. The age of onset is at puberty, and the disorder is progressive until the 3 rd -4 th decade of life...

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Bibliographic Details
Main Authors: Nallathambi Jeyabalan, Rohit Shetty, Anuprita Ghosh, Venkata Ramana Anandula, Arka Subhra Ghosh, Govindasamy Kumaramanickavel
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Epidemiology
keratoconus
prevalence
Disease pathogenesis
genetic heterogeneity
genetics and genomics
genome-wide association study
genomic loci
linkage mapping
molecular mechanisms
whole exome-genome sequencing
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=8;spage=384;epage=388;aulast=Jeyabalan

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http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=8;spage=384;epage=388;aulast=Jeyabalan

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