A Genetic Screen for Mutants with Supersized Lipid Droplets in Caenorhabditis elegans

A Genetic Screen for Mutants with Supersized Lipid Droplets in Caenorhabditis elegans

To identify genes that regulate the dynamics of lipid droplet (LD) size, we have used the genetically tractable model organism Caenorhabditis elegans, whose wild-type LD population displays a steady state of size with an upper limit of 3 μm in diameter. From a saturated forward genetic screen of 6.7...

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Bibliographic Details
Main Authors: Shiwei Li, Shibin Xu, Yanli Ma, Shuang Wu, Yu Feng, Qingpo Cui, Lifeng Chen, Shuang Zhou, Yuanyuan Kong, Xiaoyu Zhang, Jialei Yu, Mengdi Wu, Shaobing O. Zhang
Format: Article
Language:English
Published: Oxford University Press 2016-08-01
Series:G3: Genes, Genomes, Genetics
Subjects:
C. elegans
lipid droplet
peroxisome
forward genetic screen
drop
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.030866

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.030866

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