Lymphocyte subset expression and serum concentrations of PD-1/PD-L1 in sepsis - pilot study

Lymphocyte subset expression and serum concentrations of PD-1/PD-L1 in sepsis - pilot study

Abstract Background Sepsis remains a major cause of mortality in critical care, for which specific treatments are lacking. The dysregulated response to infection seen in sepsis includes features of lymphocyte dysfunction and exhaustion, suggesting that immune-stimulatory therapy may improve outcomes...

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Bibliographic Details
Main Authors: Julie K. Wilson, Yuan Zhao, Mervyn Singer, Jo Spencer, Manu Shankar-Hari
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Critical Care
Subjects:
Sepsis
Septic shock
Programmed death-1
Enrichment
Outcomes
Online Access:http://link.springer.com/article/10.1186/s13054-018-2020-2

Internet

http://link.springer.com/article/10.1186/s13054-018-2020-2

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