Dietary Apigenin Exerts Immune-Regulatory Activity in Vivo by Reducing NF-κB Activity, Halting Leukocyte Infiltration and Restoring Normal Metabolic Function

Dietary Apigenin Exerts Immune-Regulatory Activity in Vivo by Reducing NF-κB Activity, Halting Leukocyte Infiltration and Restoring Normal Metabolic Function

The increasing prevalence of inflammatory diseases and the adverse effects associated with the long-term use of current anti-inflammatory therapies prompt the identification of alternative approaches to reestablish immune balance. Apigenin, an abundant dietary flavonoid, is emerging as a potential r...

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Bibliographic Details
Main Authors: Horacio Cardenas, Daniel Arango, Courtney Nicholas, Silvia Duarte, Gerard J. Nuovo, Wei He, Oliver H. Voss, M. Elba Gonzalez-Mejia, Denis C. Guttridge, Erich Grotewold, Andrea I. Doseff
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
flavonoids
apigenin
leukocytes
NF-κB
inflammation
sepsis
mitochondria
cardiac dysfunction
Online Access:http://www.mdpi.com/1422-0067/17/3/323

Internet

http://www.mdpi.com/1422-0067/17/3/323

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