Selective TACE with irinotecan-loaded 40 μm microspheres and FOLFIRI for colorectal liver metastases: phase I dose escalation pharmacokinetic study

Selective TACE with irinotecan-loaded 40 μm microspheres and FOLFIRI for colorectal liver metastases: phase I dose escalation pharmacokinetic study

Abstract Background Efficacy of treatments for colorectal liver metastases after failure of first-line chemotherapy is limited. The aim of this study was to prospectively evaluate the feasibility, tolerability, and pharmacokinetics of selective transarterial chemoembolization (TACE) with irinotecan-...

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Bibliographic Details
Main Authors: Toshihiro Tanaka, Takeshi Sato, Hideyuki Nishiofuku, Tetsuya Masada, Shota Tatsumoto, Nagaaki Marugami, Toshio Otsuji, Masatoshi Kanno, Fumikazu Koyama, Masayuki Sho, Kimihiko Kichikawa
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Cancer
Subjects:
Liver
Neoplasm metastasis
Hepatic artery
Microspheres
Online Access:http://link.springer.com/article/10.1186/s12885-019-5862-3

Internet

http://link.springer.com/article/10.1186/s12885-019-5862-3

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