Amyloid-Beta Induces Different Expression Pattern of Tissue Transglutaminase and Its Isoforms on Olfactory Ensheathing Cells: Modulatory Effect of Indicaxanthin

Amyloid-Beta Induces Different Expression Pattern of Tissue Transglutaminase and Its Isoforms on Olfactory Ensheathing Cells: Modulatory Effect of Indicaxanthin

Herein, we assessed the effect of full native peptide of amyloid-beta (Aβ) (1-42) and its fragments (25-35 and 35-25) on tissue transglutaminase (TG2) and its isoforms (TG2-Long and TG2-Short) expression levels on olfactory ensheathing cells (OECs). Vimentin and glial fibrillary acid protein (GFAP)...

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Bibliographic Details
Main Authors: Agata Campisi, Giuseppina Raciti, Giovanni Sposito, Rosaria Grasso, Maria A. Chiacchio, Michela Spatuzza, Alessandro Attanzio, Ugo Chiacchio, Luisa Tesoriere, Mario Allegra, Rosalia Pellitteri
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
tissue transglutaminase
olfactory ensheathing cells
amyloid-beta
oxidative stress
Indicaxanthin
self-renewal
Online Access:https://www.mdpi.com/1422-0067/22/7/3388

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https://www.mdpi.com/1422-0067/22/7/3388

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