Ganglioside Alters Phospholipase Trafficking, Inhibits NF-κB Assembly, and Protects Tight Junction Integrity

Ganglioside Alters Phospholipase Trafficking, Inhibits NF-κB Assembly, and Protects Tight Junction Integrity

Background and Aims: Dietary gangliosides are present in human milk and consumed in low amounts from organ meats. Clinical and animal studies indicate that dietary gangliosides attenuate signaling processes that are a hallmark of inflammatory bowel disease (IBD). Gangliosides decrease pro-inflammato...

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Bibliographic Details
Main Authors: John J. Miklavcic, Qun Li, Jordan Skolnick, Alan B. R. Thomson, Vera C. Mazurak, Micheal Tom Clandinin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Nutrition
Subjects:
crohn
nutrition
ulcerative colitis
sphingolipid
immunology
inflammatory bowel disease
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2021.705172/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2021.705172/full

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