15-Lipoxygenase-1 biosynthesis of 7S,14S-diHDHA implicates 15-lipoxygenase-2 in biosynthesis of resolvin D5[S]
The two oxylipins 7S,14S-dihydroxydocosahexaenoic acid (diHDHA) and 7S,17S-diHDHA [resolvin D5 (RvD5)] have been found in macrophages and infectious inflammatory exudates and are believed to function as specialized pro-resolving mediators (SPMs). Their biosynthesis is thought to proceed through sequ...
Main Authors: | Steven C. Perry, Chakrapani Kalyanaraman, Benjamin E. Tourdot, William S. Conrad, Oluwayomi Akinkugbe, John Cody Freedman, Michael Holinstat, Matthew P. Jacobson, Theodore R. Holman |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-07-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520435862 |
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