Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression.

Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression.

Omega-6 (n-6) and omega-3 (n-3) long (≥ 20 carbon) chain polyunsaturated fatty acids (LC-PUFAs) play a critical role in human health and disease. Biosynthesis of LC-PUFAs from dietary 18 carbon PUFAs in tissues such as the liver is highly associated with genetic variation within the fatty acid desat...

Full description

Bibliographic Details
Main Authors: Lindsay M Reynolds, Timothy D Howard, Ingo Ruczinski, Kanika Kanchan, Michael C Seeds, Rasika A Mathias, Floyd H Chilton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5874031?pdf=render

Internet

http://europepmc.org/articles/PMC5874031?pdf=render

Similar Items