RNase L mediated protection from virus induced demyelination.

RNase L mediated protection from virus induced demyelination.

IFN-alpha/beta plays a critical role in limiting viral spread, restricting viral tropism and protecting mice from neurotropic coronavirus infection. However, the IFN-alpha/beta dependent mechanisms underlying innate anti-viral functions within the CNS are poorly understood. The role of RNase L in vi...

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Bibliographic Details
Main Authors: Derek D C Ireland, Stephen A Stohlman, David R Hinton, Parul Kapil, Robert H Silverman, Roscoe A Atkinson, Cornelia C Bergmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2745574?pdf=render

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http://europepmc.org/articles/PMC2745574?pdf=render

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