The OmpA-like protein Loa22 is essential for leptospiral virulence.

Pathogenic mechanisms of Leptospira interrogans, the causal agent of leptospirosis, remain largely unknown. This is mainly due to the lack of tools for genetic manipulations of pathogenic species. In this study, we characterized a mutant obtained by insertion of the transposon Himar1 into a gene enc...

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Bibliographic Details
Main Authors: Paula Ristow, Pascale Bourhy, Flávia Weykamp da Cruz McBride, Claudio Pereira Figueira, Michel Huerre, Patrick Ave, Isabelle Saint Girons, Albert I Ko, Mathieu Picardeau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1914066?pdf=render