Tailor-made biocatalysts: combining thermodynamics, organic synthesis, molecular biology, biochemistry and microbiology for the design of enzyme selections
A general strategy for the isolation of catalysts for given chemical reactions was designed.A first link between genes and their corresponding proteins was established by phage display: using Darwin’s principles on evolution based on selection and amplification, rare protein molecules can then be se...
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Format: | Article |
Language: | English |
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Elsevier
2012-09-01
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Series: | Computational and Structural Biotechnology Journal |
Online Access: | http://journals.sfu.ca/rncsb/index.php/csbj/article/view/csbj.201209013 |