Serum Matrix Metalloproteinase-7 Level is Associated with Fibrosis and Renal Survival in Patients with IgA Nephropathy

Serum Matrix Metalloproteinase-7 Level is Associated with Fibrosis and Renal Survival in Patients with IgA Nephropathy

Background/Aims: In view of the latest findings that matrix metalloproteinase-7 (MMP-7) acted as a vital marker and pathogenic mediator of renal fibrosis in a murine model, we hypothesized that serum MMP-7 level might serve as a noninvasive prognostic biomarker in IgA nephropathy (IgAN) patients. Me...

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Bibliographic Details
Main Authors: Jian Zhang, Pingping Ren, Yucheng Wang, Shi Feng, Cuili Wang, Xiujin Shen, Chunhua Weng, Xiaobing Lang, Zhiming Chen, Hong Jiang, Jianghua Chen
Format: Article
Language:English
Published: Karger Publishers 2017-09-01
Series:Kidney & Blood Pressure Research
Subjects:
IgA nephropathy
Matrix metalloproteinase-7
Noninvasive
Renal fibrosis
Kidney disease progression
Online Access:http://www.karger.com/Article/FullText/477132

Internet

http://www.karger.com/Article/FullText/477132

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